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Open Regulatory Competition Download Page
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Run the Open Regulatory Competition
Don't need instructions? Run ORC now!
About ORC:
The Open Regulatory Competition (ORC) is a system designed to allow researchers interested in gene transcription and regulation to run and compare suites of predictive programs distributed across the Internet. There is no barrier to adding new programs to ORC or to removing existing programs from ORC. Programs are added by individual users and labs using the Chinook peer-to-peer bioinformatics platform. ORC is designed to add new selection pressure to the multitude of gene regulation programs that currently exist by allowing any researcher to easily compare their control data to the results that are generated from in silico analysis. Thereby, allowing a researcher to adopt an algorithm with suitable performance for their genome of interest. For more information, see the ORCWiki
Testing ORC
To test out ORC use the GFF and Fasta file here. test.gff and test.fa. These will be your primary inputs. NOTE: Some programs require extra data that you may have to generate for instance a background file in Motifsampler. For testing purposes, ignore these types of programs. (They will give you warnings on the second form that more data is required).
License:
The Open Regulatory Competition (aka ORC) is open-source licenced under the (Lesser GNU Public License) LGPL and copyright Stephen Montgomery, 2005
Download:
Download the ORC war file and source here Configure the orc-config.xml to point to the root directory of the ORC installation and restart Tomcat.
Services should start appearing after ~5-10 seconds. The ORC war and zip files are made using Apache ANT.
Contact:
Contact chinook@bcgsc.bc.ca or use the wiki for support
Statistics in ORC
Sensitivity, Specificity, Positive Predictive Value, Correlation Coefficient, and a table-based analysis of Correlation Coefficient for pairs of predictive tools. For an example of the latter, check out this image.
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